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A phase II clinical study evaluating Bermekimab in patients with moderate to severe Hidradenitis Suppurativa is underway. — A physician-sponsored …



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Hidradenitis Suppurativa Market Analysis and Forecast to 2023 by Recent Trends, Developments in Manufacturing Technology and Regional Growth Overview


Global Hidradenitis Suppurativa Market: Report evaluates the growth rate and the Market value based on Market dynamics, growth inducing factors. The complete knowledge is based on latest industry news, opportunities and trends. The report contains a comprehensive Market analysis and vendor landscape in addition to a SWOT analysis of the key vendors.

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The report firstly introduced the Hidradenitis Suppurativa Market basics: definitions, classifications, applications and market overview; product specifications; manufacturing processes; cost structures, raw materials and so on. Then it analyzed the world’s main region market conditions, including the product price, profit, capacity, production, supply, demand and market growth rate and forecast etc. In the end, the report introduced new project SWOT analysis, investment feasibility analysis, and investment return analysis.

The Global Hidradenitis Suppurativa Market report provides in-depth information about Hidradenitis Suppurativa industry, definition, classification, application, industry chain structure, industry overview; international market analysis. This report studies sales (consumption) of Hidradenitis Suppurativa market, focuses on the top players, with sales, price, revenue and market share with volume and value for each region.

Global Hidradenitis Suppurativa Market by Region:

  • China
  • Japan
  • South Korea
  • Taiwan
  • India
  • Southeast Asia
  • Australia

Global Hidradenitis Suppurativa Market by Application:

  • Application 1
  • Application 2
  • Application 3
  • Application 4
  • Application 5

Global Hidradenitis Suppurativa Market by Product Type:

  • Type 1
  • Type 2
  • Type 3
  • Type 4
  • Type 5

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After the basic information, the Hidradenitis Suppurativa Market report sheds light on the production. Production plants, their capacities, Asia-Pacific production and revenue are studied. Also, the Hidradenitis Suppurativa market growth in various regions and R&D status are also covered.

To provide information on competitive landscape, this report includes detailed profiles of major key players of Hidradenitis Suppurativa Industry:

  • Company 1
  • Company 2
  • Company 3
  • Company 4
  • Company 5
  • Company 6…. And More

The Hidradenitis Suppurativa market report discovers for each player, product details, capacity, price, cost, gross and revenue numbers are given. Their contact information is provided for better understanding.
In this Hidradenitis Suppurativa industry analysis, traders and distributors analysis is given along with contact details. For material and equipment suppliers also, contact details are given. New investment feasibility analysis is included in the Hidradenitis Suppurativa Market report.

Following are major Table of Content of Hidradenitis Suppurativa Market Report:

  1. Industry Overview of Hidradenitis Suppurativa.
  2. Two Hidradenitis Suppurativa Up and Down Stream Industry Analysis
  3. Three  Hidradenitis Suppurativa Market Analysis.
  4. Four 2013-2018 Hidradenitis Suppurativa Productions Supply Sales Demand Market Status and Forecas.
  5. Price, Cost, Gross and Gross Margin Analysis of Hidradenitis Suppurativa by Regions, Types and Manufacturers.
  6. Consumption Volume, Consumption Value and Sale Price Analysis of Hidradenitis Suppurativa industry by Regions, Types and Applications.
  7. Supply, Import, Export and Consumption Analysis of Hidradenitis Suppurativa Market.
  8. Major Manufacturers Analysis of Hidradenitis Suppurativa industry.
  9. Marketing Trader or Distributor Analysis of Hidradenitis Suppurativa.
  10. Industry Chain Analysis of Hidradenitis Suppurativa.
  11. Development Trend Analysis of Hidradenitis Suppurativa Market.
  12. New Project Investment Feasibility Analysis of Hidradenitis Suppurativa.
  13. Conclusion of the Hidradenitis Suppurativa Industry.


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AbbVie Reinforces Leadership in Dermatology With New Data Showcasing Research Advancements Across Growing Portfolio at the 27th European Academy of Dermatology and Venereology (EADV) Congress


NORTH CHICAGO, Ill., Sept. 4, 2018 /PRNewswire/ — AbbVie (NYSE : ABBV ), a research-based global biopharmaceutical company, today announced that it will present new data across investigational medicines and HUMIRA® (adalimumab) at the 27th European Academy of Dermatology and Venereology (EADV) Congress, September 12-16, in Paris.

“While there have been significant advances in the treatment of serious dermatologic diseases in recent years, some patients still do not achieve their desired treatment goals and are in need of additional effective therapeutic options,” said Marek Honczarenko M.D., P.h.D., vice president, global immunology development, AbbVie. “AbbVie’s data at EADV reflect our unwavering commitment to addressing these ongoing therapeutic challenges for patients and our continued pursuit of innovative medicines that raise treatment expectations and improve upon the standard of care.”

AbbVie will present data from three pivotal Phase 3 trials of risankizumab, an investigational interleukin-23 (IL-23) inhibitor, in patients with moderate to severe psoriasis, including first presentation of the full data results from the IMMvent trial as well as patient-reported outcomes results from ultIMMa-1, ultIMMa-2 and IMMvent.

Additional patient-reported outcomes data from a Phase 2b trial evaluating upadacitinib, an investigational JAK1 inhibitor, in atopic dermatitis will be featured as an oral presentation on Thursday, September 13 at 3:20 p.m. CEST. In addition, efficacy and safety results at week 32 of the Phase 2b trial will be presented.

Risankizumab and upadacitinib are not approved by regulatory authorities and safety and efficacy have not been established.

AbbVie will also share long-term efficacy and safety results evaluating HUMIRA in hidradenitis suppurativa (HS) during an oral presentation. Data reporting long-term inhibition of radiographic progression with HUMIRA in psoriatic arthritis will also be featured as an oral ePoster presentation, along with real-world long-term safety and effectiveness data that further support the real-world value of HUMIRA for the treatment of moderate to severe psoriasis.

HUMIRA is one of the most comprehensively-studied biologics available for immune-mediated diseases, and is supported by more than 20 years of clinical trial experience in immunology.1

Key Abstracts of Interest

Risankizumab Abstracts

  • Efficacy and Safety of Risankizumab Compared with Adalimumab in Patients with Moderate-to-Severe Plaque Psoriasis: Results from the Phase 3 IMMvent Trial; ePoster #P1813
  • Efficacy and Safety of Risankizumab Compared with Placebo in Patients with Moderate-to-Severe Plaque Psoriasis: Integrated Analyses from Three Phase 3 Trials; ePoster #P1865
  • Efficacy of Risankizumab Compared with Placebo Across Subgroups in Patients with Moderate-to-Severe Plaque Psoriasis: Integrated Analyses from Three Phase 3 Trials; Oral ePoster #OP01.04; Oral ePoster presentations in Therapies; Thursday, September 13; 10:15-10:25 a.m. CEST
  • Incremental benefits on patient-reported outcomes for achieving PASI90 or PASI100 over PASI75 in patients with moderate to severe psoriasis; ePoster #P2002
  • Patient-Reported Outcomes from the IMMVent Trial: Comparison of Risankizumab with Adalimumab in Moderate to Severe Psoriasis Patients; ePoster #P1947
  • Risankizumab Significantly Improves Patient-Reported Outcomes in Moderate to Severe Psoriasis in Two Phase III ultIMMa Trials; ePoster #P1996

Upadacitinib Abstracts

  • Effects of Upadacitinib on Patient-Reported Itch, Skin Pain, and Impact on Sleep Due to Atopic Dermatitis: Results From the Phase 2b Randomized, Placebo-Controlled Trial in Moderate-to-Severe Atopic Dermatitis; Presentation #FC04.03; Free Communications in Therapy; Thursday, September 13; 3:20-3:30 p.m. CEST
  • Effects of Upadacitinib on Scratching and Activity During Sleep as Evaluated by Actigraphy in the Phase 2b Randomized, Placebo-Controlled Trial in Moderate-to-Severe Atopic Dermatitis; ePoster #P0235
  • Efficacy and Safety of Upadacitinib Treatment over 32 weeks for Patients with Atopic Dermatitis from a Phase 2b, Randomized, Placebo-Controlled Trial; ePoster #P0236

HUMIRA Abstracts

Psoriasis

  • Long-term Real-World Safety and Effectiveness of Adalimumab for Moderate to Severe Psoriasis: Results from the Nine-Year Interim Analysis of the ESPRIT Registry; ePoster #P1942
  • Sustained Response to Adalimumab Over Multiple Years in Patients With Plaque Psoriasis: Analyses From the British Association of Dermatologists’ Biological Interventions Register; ePoster #P2039

Hidradenitis suppurativa (HS)

  • Weekly Adalimumab in Patients with Moderate-to-Severe Hidradenitis Suppurativa Following Loss of Response, or Worsening or Absence of Improvement; Presentation #FC04.02; Free Communications in Therapy; Thursday, September 13; 3:10-3:20 p.m. CEST
  • Indirect economic burden associated with multiple and more complex surgical procedures for hidradenitis suppurativa; Presentation #FC05.04; Free Communications in Acne and Related Disorders; Saturday, September 15, 8:30-8:40 a.m. CEST

Psoriatic Arthritis

  • Long-term Inhibition of Radiographic Progression With Adalimumab in Patients With Moderate to Severe Psoriatic Arthritis With or Without Radiographic Damage at Baseline; Oral ePoster #OP01.02; Oral e-Poster Presentations in Therapies; Thursday, September 13; 9:55-10:05 a.m. CEST

About Upadacitinib

Discovered and developed by AbbVie, upadacitinib is an investigational oral agent engineered to selectively inhibit JAK1, which plays an important role in the pathophysiology of immune-mediated disorders.2,3 Phase 3 trials of upadacitinib in rheumatoid arthritis, psoriatic arthritis and Crohn’s disease are ongoing and it is also being investigated to treat ulcerative colitis, ankylosing spondylitis and atopic dermatitis.4,5,6,7,8

Upadacitinib is an investigational medicine and is not approved by regulatory authorities. Safety and efficacy have not been established.

About Risankizumab

Risankizumab is an investigational compound that selectively blocks IL-23 by binding to its p19 subunit.9 IL-23, a cytokine involved in inflammatory processes, is thought to be linked to a number of chronic immune-mediated diseases.10 Phase 3 trials of risankizumab in psoriasis and Crohn’s disease are ongoing, and it is also being investigated to treat psoriatic arthritis and ulcerative colitis.3,11,12,13,14

Risankizumab is part of a collaboration between Boehringer Ingelheim and AbbVie, with AbbVie leading future development and commercialization of risankizumab globally. It is an investigational medicine and is not approved by regulatory authorities. Safety and efficacy have not been established.

About HUMIRA in the European Union15

HUMIRA EU Therapeutic Indications

HUMIRA is approved for use in adults with moderate to severe active and progressive rheumatoid arthritis, severe active ankylosing spondylitis (AS), severe axial spondyloarthritis without radiographic evidence of AS, moderate to severe chronic plaque psoriasis, active and progressive psoriatic arthritis, moderately to severely active Crohn’s disease, moderately to severely active ulcerative colitis and non-infectious intermediate, posterior and panuveitis in adults. HUMIRA is approved for use in adults and adolescents from 12 years of age with active moderate to severe hidradenitis suppurativa, and in pediatric patients with active enthesitis-related arthritis, severe chronic plaque psoriasis, chronic non-infectious anterior uveitis, moderately to severely active Crohn’s disease, and active polyarticular juvenile idiopathic arthritis. See Summary of Product Characteristics (SmPC) for full indications.

Important EU Safety Information

HUMIRA is contraindicated in patients with active tuberculosis or other severe infections such as sepsis, and opportunistic infections and in patients with moderate to severe heart failure (NYHA class III/IV). It is also contraindicated in patients hypersensitive to the active substance or to any of the excipients. The use of HUMIRA increases the risk of developing serious infections which may, in rare cases, be life-threatening. Rare cases of lymphoma and leukemia have been reported in patients treated with HUMIRA. On rare occasions, a severe type of cancer called hepatosplenic T-cell lymphoma has been observed and often results in death. A risk for the development of malignancies in patients treated with TNF-antagonists cannot be excluded. The most frequently reported adverse events across all indications included respiratory infections, injection site reactions, headache and musculoskeletal pain.

Globally, prescribing information varies; refer to the individual country product label for complete information.

Full summary of product characteristics is available at: www.ema.europa.eu

For more information about JAK inhibitors and AbbVie’s research in atopic dermatitis, please read “What Makes the Immune System Compromise Your Health?” on www.abbvie.com.

For more information on IL-23 and AbbVie’s psoriasis research, please read “Gone Rogue: What Happens When Cells Say the Wrong Thing” on www.abbvie.com.

About AbbVie

AbbVie is a global, research and development-based biopharmaceutical company committed to developing innovative advanced therapies for some of the world’s most complex and critical conditions. The company’s mission is to use its expertise, dedicated people and unique approach to innovation to markedly improve treatments across four primary therapeutic areas: immunology, oncology, virology and neuroscience. In more than 75 countries, AbbVie employees are working every day to advance health solutions for people around the world. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook or LinkedIn.

Forward-Looking Statements

Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The words “believe,” “expect,” “anticipate,” “project” and similar expressions, among others, generally identify forward-looking statements. AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those indicated in the forward-looking statements. Such risks and uncertainties include, but are not limited to, challenges to intellectual property, competition from other products, difficulties inherent in the research and development process, adverse litigation or government action, and changes to laws and regulations applicable to our industry. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie’s operations is set forth in Item 1A, “Risk Factors,” of AbbVie’s 2017 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission. AbbVie undertakes no obligation to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law.

1 Burmester G.R., et al. Adalimumab safety and mortality rates from global clinical trials of six immune-mediated inflammatory diseases Ann Rheum Dis. 2009;68:1863–1869.

2 Voss, J, et al; Pharmacodynamics Of a Novel Jak1 Selective Inhibitor In Rat Arthritis and Anemia Models and In Healthy Human Subjects. [abstract]. Arthritis Rheum 2013;65 Suppl 10 :2374. DOI: 10.1002/art.2013.65.issue-s10

3 Pipeline – Our Science | AbbVie. Available at: https://www.abbvie.com/our-science/pipeline.html. Accessed on June 26, 2018.

4 A Study Comparing ABT-494 to Placebo in Subjects With Rheumatoid Arthritis on a Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response to csDMARDs Alone (SELECT-NEXT). ClinicalTrials.gov. Available at: https://clinicaltrials.gov/ct2/show/NCT02675426. Accessed on June 26, 2018.

5 A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Participants With Psoriatic Arthritis Who Have an Inadequate Response to at Least One Non-Biologic Disease Modifying Anti-Rheumatic Drug (SELECT – PsA 1). ClinicalTrials.gov. Available at: https://clinicaltrials.gov/ct2/show/NCT03104400. Accessed on June 26, 2018.

6 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn’s Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy. ClinicalTrials.gov. Available at: https://clinicaltrials.gov/ct2/show/NCT02365649. Accessed on June 26, 2018.

7 Phase 2b AD Dose Ranging Study (40wk) N=160Clinicaltrialsgov. Available at: https://clinicaltrials.gov/ct2/show/NCT02925117. Accessed on June 26, 2018.

8 A Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis. ClinicalTrials.gov. Available at: https://clinicaltrials.gov/ct2/show/NCT02819635. Accessed on June 26, 2018.

9 Papp K.A., et al. Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis. NEJM. 2017.

10 Duvallet E, Sererano L, Assier E, et. al. Interleukin-23: a key cytokine in inflammatory diseases. Ann Med. 2011 Nov;43(7):503-11.

11 A Study of the Efficacy and Safety of Risankizumab in Subjects With Moderately to Severely Active Crohn’s Disease. ClinicalTrials.gov. Available at: https://clinicaltrials.gov/ct2/show/NCT03105128. Accessed on June 26, 2018.

12 BI 655066/ABBV-066/Risankizumab Compared to Placebo in Patients With Active Psoriatic Arthritis. ClinicalTrials.gov. Available at: https://clinicaltrials.gov/ct2/show/NCT02719171. Accessed on June 26, 2018.

13 A Study to Assess the Efficacy and Safety of Risankizumab in Subjects With Ulcerative Colitis Who Responded to Induction Treatment in M16-067 or M16-065. ClinicalTrials.gov. 2018. https://www.clinicaltrials.gov/ct2/show/NCT03398135. Accessed on June 26, 2018.

14 A Study to Evaluate the Efficacy and Safety of Risankizumab in Subjects With Moderately to Severely Active Ulcerative Colitis Who Have Failed Prior Biologic Therapy. ClinicalTrials.gov. 2018. https://www.clinicaltrials.gov/ct2/show/NCT03398148. Accessed on June 26, 2018.

15 HUMIRA [Summary of Product Characteristics]. AbbVie Ltd.; Available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000481/WC500050870.pdf. Last updated July 2018. Accessed July 31, 2018.

SOURCE AbbVie

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Chemocentryx (CCXI) Holder P-A-W Capital Cut Its Holding as Valuation Rose; Zendesk (ZEN) Shareholder Crosslink Capital Has Decreased Position by $26.97 Million as Share Value Rose




August 30, 2018 – By Estela Ashley

ChemoCentryx, Inc. (NASDAQ:CCXI) Logo

P-A-W Capital Corp decreased its stake in Chemocentryx Inc (CCXI) by 53.13% based on its latest 2018Q1 regulatory filing with the SEC. P-A-W Capital Corp sold 85,000 shares as the company’s stock rose 32.26% while stock markets declined. The hedge fund held 75,000 shares of the health care company at the end of 2018Q1, valued at $1.02 million, down from 160,000 at the end of the previous reported quarter. P-A-W Capital Corp who had been investing in Chemocentryx Inc for a number of months, seems to be less bullish one the $645.85M market cap company. The stock increased 0.47% or $0.06 during the last trading session, reaching $12.82. About 12,425 shares traded. ChemoCentryx, Inc. (NASDAQ:CCXI) has risen 83.50% since August 30, 2017 and is uptrending. It has outperformed by 70.93% the S&P500. Some Historical CCXI News: 22/03/2018 – ChemoCentryx Publishes Novel Findings of Role of CCR2 in Kidney Glomerulus, Supporting Advancement of CCR2 Inhibitor CCX140 in the Treatment of Focal Segmental Glomerulosclerosis (FSGS); 09/03/2018 ChemoCentryx 4Q EPS 80c; 09/03/2018 – CCXI TO BEGIN AVACOPAN CLINICAL STUDIES IN HS BY ’18 END; 10/05/2018 – Invus Public Equities Advisors Exits Position in ChemoCentryx; 11/04/2018 – ChemoCentryx Announces Presentation During National Kidney Foundation 2018 Spring Clinical Meeting; 23/05/2018 – ChemoCentryx Announces Two Upcoming Presentations at the 55th ERA-EDTA Congress; 20/04/2018 – DJ Chemocentryx Inc, Inst Holders, 1Q 2018 (CCXI); 09/03/2018 – ChemoCentryx 4Q Net $39.7M; 13/03/2018 – CHEMOCENTRYX INC CCXI.O : JP MORGAN RAISES TARGET PRICE TO $16 FROM $13; 09/03/2018 – CCXI PLANS TO START DEVT AVACOPAN IN HIDRADENITIS SUPPURATIVA

Crosslink Capital Inc decreased its stake in Zendesk Inc (ZEN) by 72.06% based on its latest 2018Q1 regulatory filing with the SEC. Crosslink Capital Inc sold 573,742 shares as the company’s stock rose 30.39% while stock markets declined. The hedge fund held 222,456 shares of the technology company at the end of 2018Q1, valued at $10.65 million, down from 796,198 at the end of the previous reported quarter. Crosslink Capital Inc who had been investing in Zendesk Inc for a number of months, seems to be less bullish one the $7.34B market cap company. The stock increased 0.09% or $0.06 during the last trading session, reaching $69.29. About 118,457 shares traded. Zendesk, Inc. (NYSE:ZEN) has risen 119.18% since August 30, 2017 and is uptrending. It has outperformed by 106.61% the S&P500. Some Historical ZEN News: 08/03/2018 ZENDESK INC ZEN.N : UBS RAISES TARGET PRICE TO $46 FROM $43; 21/05/2018 – ZENDESK INC ZEN.N : BOFA MERRILL RAISES PRICE OBJECTIVE TO $64 FROM $60; 01/05/2018 – Zendesk Sees 2018 Rev $565M-$572M; 10/05/2018 – Zendesk to Hold Annual Analyst & Investor Day on May 17, 2018; 22/03/2018 – Research Links Employee Volunteering With Happier Customers; 03/04/2018 – ZENDESK SAYS IT SURPASSES $500M ANNUAL REV. RUN RATE; 03/04/2018 – Zendesk Surpasses $500M Annual Revenue Run Rate; Continues Enterprise Expansion With New Al-Powered Enterprise Self-Service Product; 18/05/2018 – ZENDESK INC ZEN.N : CRAIG-HALLUM RAISES TARGET PRICE TO $63; 19/04/2018 – DJ Zendesk Inc, Inst Holders, 1Q 2018 (ZEN); 03/04/2018 – Zendesk: Surpasses $500M Annual Rev Run Rate

Investors sentiment decreased to 1 in Q1 2018. Its down 0.30, from 1.3 in 2017Q4. It dived, as 10 investors sold CCXI shares while 36 reduced holdings. 24 funds opened positions while 22 raised stakes. 24.22 million shares or 3.03% more from 23.51 million shares in 2017Q4 were reported. American Gru Inc stated it has 15,795 shares. 37,100 are held by New York State Common Retirement Fund. Jane Street Grp Inc Limited Company has invested 0% in ChemoCentryx, Inc. (NASDAQ:CCXI). Vanguard Group Inc holds 1.22M shares. Carmignac Gestion owns 390,097 shares. Schwab Charles Management invested 0% of its portfolio in ChemoCentryx, Inc. (NASDAQ:CCXI). Spark Mgmt Limited Liability Corp holds 0.05% of its portfolio in ChemoCentryx, Inc. (NASDAQ:CCXI) for 62,600 shares. Franklin Resource holds 0.01% or 1.69 million shares in its portfolio. Banque Pictet Cie Sa reported 54,178 shares. Panagora Asset owns 369,959 shares. Acadian Asset Mgmt Ltd Co invested in 0.03% or 521,864 shares. Wells Fargo & Commerce Mn reported 0% stake. 19,000 are held by State Of Wisconsin Invest Board. California State Teachers Retirement Systems holds 38,188 shares. 625 were reported by Thompson Davis And Com.

P-A-W Capital Corp, which manages about $83.23M US Long portfolio, upped its stake in Allot Communications Ltd (NASDAQ:ALLT) by 120,000 shares to 700,000 shares, valued at $3.77M in 2018Q1, according to the filing. It also increased its holding in Quotient Technology Inc by 70,000 shares in the quarter, for a total of 230,000 shares, and has risen its stake in Eiger Biopharmaceuticals Inc.

Among 7 analysts covering ChemoCentryx (NASDAQ:CCXI), 4 have Buy rating, 1 Sell and 2 Hold. Therefore 57% are positive. ChemoCentryx had 10 analyst reports since September 3, 2015 according to SRatingsIntel. The company was maintained on Tuesday, August 8 by Cowen & Co. The rating was maintained by JP Morgan with “Overweight” on Tuesday, March 13. The firm has “Neutral” rating by JP Morgan given on Tuesday, August 14. The stock has “Sell” rating by Zacks on Monday, September 21. On Thursday, August 10 the stock rating was maintained by JMP Securities with “Buy”. The stock of ChemoCentryx, Inc. (NASDAQ:CCXI) has “Mkt Outperform” rating given on Tuesday, February 21 by JMP Securities. As per Thursday, September 3, the company rating was downgraded by Zacks.

Analysts await ChemoCentryx, Inc. (NASDAQ:CCXI) to report earnings on November, 6. They expect $-0.25 earnings per share, down 92.31% or $0.12 from last year’s $-0.13 per share. After $-0.14 actual earnings per share reported by ChemoCentryx, Inc. for the previous quarter, Wall Street now forecasts 78.57% negative EPS growth.

Since May 1, 2018, it had 0 insider buys, and 12 selling transactions for $7.89 million activity. Cappel Markus J. had sold 50,000 shares worth $590,637. 200,000 shares were sold by Schall Thomas J., worth $2.36 million on Tuesday, May 15.

More notable recent ChemoCentryx, Inc. (NASDAQ:CCXI) news were published by: Nasdaq.com which released: “Recent Analysis Shows Ferroglobe, AXT, ChemoCentryx, RedHill Biopharma, GTx, and Achillion Pharmaceuticals …” on August 20, 2018, also Nasdaq.com with their article: “ChemoCentryx to Present at Two Upcoming Investor Conferences” published on August 22, 2018, Seekingalpha.com published: “ChemoCentryx, Inc. (CCXI) CEO Dr. Thomas Schall on Q2 2018 Results – Earnings Call Transcript” on August 10, 2018. More interesting news about ChemoCentryx, Inc. (NASDAQ:CCXI) were released by: Seekingalpha.com and their article: “ChemoCentryx 2018 Q2 – Results – Earnings Call Slides” published on August 10, 2018 as well as Globenewswire.com‘s news article titled: “ChemoCentryx Reports Second Quarter 2018 Financial Results and Recent Highlights” with publication date: August 09, 2018.

Analysts await Zendesk, Inc. (NYSE:ZEN) to report earnings on November, 7. They expect $-0.24 EPS, up 7.69% or $0.02 from last year’s $-0.26 per share. After $-0.25 actual EPS reported by Zendesk, Inc. for the previous quarter, Wall Street now forecasts -4.00% EPS growth.

Another recent and important Zendesk, Inc. (NYSE:ZEN) news was published by Seekingalpha.com which published an article titled: “Zendesk: The Streak Won’t Last Forever” on August 01, 2018.

Crosslink Capital Inc, which manages about $2.09B and $498.50 million US Long portfolio, upped its stake in Paypal Holdings by 96,070 shares to 233,410 shares, valued at $17.71 million in 2018Q1, according to the filing. It also increased its holding in Class A by 288,765 shares in the quarter, for a total of 1.59M shares, and has risen its stake in Worldpay Inc (NYSE:VNTV).

ChemoCentryx, Inc. (NASDAQ:CCXI) Institutional Positions Chart

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What’s Propelling Xbiotech Inc (NASDAQ:XBIT) After Lower Shorts Reported?




August 30, 2018 – By Lisa Delgado

XBiotech Inc. (NASDAQ:XBIT) Logo

The stock of Xbiotech Inc (NASDAQ:XBIT) registered a decrease of 1.51% in short interest. XBIT’s total short interest was 4.45 million shares in August as published by FINRA. Its down 1.51% from 4.52 million shares, reported previously. With 32,500 shares average volume, it will take short sellers 137 days to cover their XBIT’s short positions. The short interest to Xbiotech Inc’s float is 22.82%.

The stock increased 1.79% or $0.07 during the last trading session, reaching $3.97. About 2,967 shares traded. XBiotech Inc. (NASDAQ:XBIT) has declined 47.21% since August 30, 2017 and is downtrending. It has underperformed by 59.78% the S&P500.

XBiotech Inc., a clinical-stage biopharmaceutical company, engages in discovering and developing True Human monoclonal antibodies for treating various diseases. The company has market cap of $142.21 million. The company??s lead product is Xilonix, which is also known as MABp1, a therapeutic antibody that neutralizes interleukin-1 alpha, which has completed Phase III clinical trial in Europe for the treatment of symptomatic and advanced colorectal cancer. It currently has negative earnings. It has also investigating its lead product candidate in various clinical trials for other inflammatory conditions, including vascular disease, type II diabetes, acne, psoriasis, pyoderma gangrenosum, and hidradenitis suppurativa, as well as staphylococcus aureus infection, influenza, and clostridium difficile infection diseases.

More news for XBiotech Inc. (NASDAQ:XBIT) were recently published by: Nasdaq.com, which released: “XBiotech Announces Publication of Breakthrough Findings for Potential Role of Interleukin-1 alpha in Risk for Heart …” on August 27, 2018. Globenewswire.com‘s article titled: “XBiotech Highlights Quarterly Developments” and published on August 10, 2018 is yet another important article.

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